Leptin receptor q223r polymorphism influences neutrophil mobilization after Clostridium difficile infection
نویسندگان
چکیده
منابع مشابه
Effect of leptin receptor Q223R polymorphism on breast cancer risk
Objective(s):Leptin receptor (LEPR) is a member of the class I cytokine receptor super-family that is known implicated in the initiation and progression of breast cancer. We have investigated the effect of Q223R polymorphism on the breast cancer susceptibly in a sample of Iranian subjects. Materials and Methods:We utilized a polymerase chain reaction (PCR) restriction fragment length polymorphi...
متن کاملEffect of leptin receptor Q223R polymorphism on breast cancer risk
OBJECTIVES Leptin receptor (LEPR) is a member of the class I cytokine receptor super-family that is known implicated in the initiation and progression of breast cancer. We have investigated the effect of Q223R polymorphism on the breast cancer susceptibly in a sample of Iranian subjects. MATERIALS AND METHODS We utilized a polymerase chain reaction (PCR) restriction fragment length polymorphi...
متن کاملeffect of leptin receptor q223r polymorphism on breast cancer risk
objective(s):leptin receptor (lepr) is a member of the class i cytokine receptor super-family that is known implicated in the initiation and progression of breast cancer. we have investigated the effect of q223r polymorphism on the breast cancer susceptibly in a sample of iranian subjects. materials and methods:we utilized a polymerase chain reaction (pcr) restriction fragment length polymorphi...
متن کاملKinetics of Leptin Binding to the Q223R Leptin Receptor
Studies in human populations and mouse models of disease have linked the common leptin receptor Q223R mutation to obesity, multiple forms of cancer, adverse drug reactions, and susceptibility to enteric and respiratory infections. Contradictory results cast doubt on the phenotypic consequences of this variant. We set out to determine whether the Q223R substitution affects leptin binding kinetic...
متن کاملClostridium difficile Infection.
Clostridium difficile infection is a major health care challenge in terms of patient and economic consequences. For the patient, it is a morbid and sometimes a life-threatening iatrogenic complication of antibiotic treatment. In the United States, the provider's institution may face financial penalties, because the Centers for Disease Control and Prevention views this as an iatrogenic health ca...
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ژورنال
عنوان ژورنال: Mucosal Immunology
سال: 2018
ISSN: 1933-0219,1935-3456
DOI: 10.1038/mi.2017.119